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MUCH OF THE POPULATION GENETIC RISK OF COLORECTAL CANCER IS LIKELY TO BE MEDIATED THROUGH SUSCEPTIBILITY TO ADENOMAS

Several single nucleotide polymorphisms (SNPs) have been associated with colorectal cancer (CRC) susceptibility. Most CRCs arise from adenomas, and SNPs might therefore affect predisposition to CRC by increasing adenoma risk. We found that 8 of 18 known CRC-associated SNPs (rs10936599, rs6983267, rs...

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Bibliographische Detailangaben
Hauptverfasser: Carvajal-Carmona, Luis G., Zauber, Ann G., Jones, Angela M., Howarth, Kimberley, Wang, Jiping, Cheng, Timothy, Riddell, Robert, Lanas, Angel, Morton, Dion, Bertagnolli, Monica M., Tomlinson, Ian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572711/
https://ncbi.nlm.nih.gov/pubmed/22999960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.09.016
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