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Nigral GFRα1 Infusion in Aged Rats Increases Locomotor Activity, Nigral Tyrosine Hydroxylase, and Dopamine Content in Synchronicity

Delivery of exogenous glial cell line-derived neurotrophic factor (GDNF) increases locomotor activity in rodent models of aging and Parkinson’s disease in conjunction with increased dopamine (DA) tissue content in substantia nigra (SN). Striatal GDNF infusion also increases expression of GDNF’s cogn...

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Detalhes bibliográficos
Main Authors: Pruett, Brandon S., Salvatore, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037235/
https://ncbi.nlm.nih.gov/pubmed/23321789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-013-8397-7
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