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Tyrosine Hydroxylase and Regulation of Dopamine Synthesis
Tyrosine hydroxylase is the rate-limiting enzyme of catecholamine biosynthesis; it uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to DOPA. Its amino terminal 150 amino acids comprise a domain whose structure is involved in regulating the enzyme’s activity. Modes of regulation incl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065393/ https://ncbi.nlm.nih.gov/pubmed/21176768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.12.017 |
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