Impairment of Nitric Oxide Synthase but Not Heme Oxygenase Accounts for Baroreflex Dysfunction Caused by Chronic Nicotine in Female Rats

We recently reported that chronic nicotine impairs reflex chronotropic activity in female rats. Here, we sought evidence to implicate nitric oxide synthase (NOS) and/or heme oxygenase (HO) in the nicotine-baroreflex interaction. Baroreflex curves relating changes in heart rate to increases (phenylep...

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Detalhes bibliográficos
Main Authors: Fouda, Mohamed A., El-Gowelli, Hanan M., El-Gowilly, Sahar M., Rashed, Laila, El-Mas, Mahmoud M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037226/
https://ncbi.nlm.nih.gov/pubmed/24870610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098681
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