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Achieving Peptide Binding Specificity and Promiscuity by Loops: Case of the Forkhead-Associated Domain

The regulation of a series of cellular events requires specific protein–protein interactions, which are usually mediated by modular domains to precisely select a particular sequence from diverse partners. However, most signaling domains can bind to more than one peptide sequence. How do proteins cre...

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Detalhes bibliográficos
Main Authors: Huang, Yu-ming M., Chang, Chia-en A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037201/
https://ncbi.nlm.nih.gov/pubmed/24870410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098291
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