High titers of autoantibodies to glutamate decarboxylase in Type 1 Diabetes Patients: Epitope Analysis and Inhibition of Enzyme Activity

OBJECTIVE: Autoantibodies to glutamate decarboxylase (GAD65Ab) are found in patients with autoimmune neurological disorders and patients with type 1 diabetes. The correct diagnosis of GAD65Ab-associated neurological disorders is often delayed by the variability of symptoms and a lack of diagnostic m...

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Main Authors: Hampe, Christiane S., Maitland, Murray E., Gilliam, Lisa K., Thi Phan, Thanh-H., Sweet, Ian R., Radtke, Jared R., Bota, Vasile, Ransom, Bruce R., Hirsch, Irl B.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037149/
https://ncbi.nlm.nih.gov/pubmed/23512385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4158/EP12318.OR
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