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Does the APC/C Mark MIWI and piRNAs for a Final Farewell?

Recently in Developmental Cell, Zhao et al. (2013) reported a mechanism for the directed turnover of the mouse Piwi protein MIWI during sperm maturation. This study implicates the anaphase-promoting complex as a mediator of MIWI ubiquitination and expands the avenues for regulating small RNA process...

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Autors principals: Sytnikova, Yuliya, Lau, Nelson C.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036799/
https://ncbi.nlm.nih.gov/pubmed/23369709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.01.005
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