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Functional Divergence of Two Zebrafish Midkine Growth Factors Following Fish-Specific Gene Duplication
In mammals, the unique midkine (mdk) gene encodes a secreted heparin-binding growth factor with neurotrophic activity. Here, we show the presence of two functional mdk genes named mdka and mdkb in zebrafish and rainbow trout. Both midkine proteins are clearly different from the related pleiotrophin,...
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| Päätekijät: | , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Cold Spring Harbor Laboratory Press
2003
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC403662/ https://ncbi.nlm.nih.gov/pubmed/12743018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1097503 |
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