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Posttranscriptional clearance of hepatitis B virus RNA by cytotoxic T lymphocyte-activated hepatocytes.

Using transgenic mice that replicate the hepatitis B virus (HBV) genome, we recently demonstrated that class I-restricted, hepatitis B surface antigen-specific cytotoxic T lymphocytes (CTLs) can noncytolytically eliminate HBV pregenomic and envelope RNA transcripts from the hepatocyte. We now demons...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Tsui, L V, Guidotti, L G, Ishikawa, T, Chisari, F V
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8618909/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.26.12398
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