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High-level hepatitis B virus replication in transgenic mice.

Hepatitis B virus (HBV) transgenic mice whose hepatocytes replicate the virus at levels comparable to that in the infected livers of patients with chronic hepatitis have been produced, without any evidence of cytopathology. High-level viral gene expression was obtained in the liver and kidney tissue...

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Detalhes bibliográficos
Main Authors: Guidotti, L G, Matzke, B, Schaller, H, Chisari, F V
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC189513/
https://ncbi.nlm.nih.gov/pubmed/7666518
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