High-level hepatitis B virus replication in transgenic mice.

Hepatitis B virus (HBV) transgenic mice whose hepatocytes replicate the virus at levels comparable to that in the infected livers of patients with chronic hepatitis have been produced, without any evidence of cytopathology. High-level viral gene expression was obtained in the liver and kidney tissue...

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Pubblicato in:	J Virol
Autori principali:	Guidotti, L G, Matzke, B, Schaller, H, Chisari, F V
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189513/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7666518/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.10.6158-6169.1995
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