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In vitro clinical trials: the future of cell-based profiling

The drug discovery process classically revolves around a set of biochemical and cellular assays to drive potency optimization and structural-activity relationship models. Layered on top of these concepts is the inclusion of molecular features that affect final drug use, things like: bioavailability,...

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Detalhes bibliográficos
Main Authors: Ross, Nathan T., Wilson, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036381/
https://ncbi.nlm.nih.gov/pubmed/24904423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00121
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