High Glucose-induced O-GlcNAcylated Carbohydrate Response Element-binding Protein (ChREBP) Mediates Mesangial Cell Lipogenesis and Fibrosis: THE POSSIBLE ROLE IN THE DEVELOPMENT OF DIABETIC NEPHROPATHY

Carbohydrate response element-binding protein (ChREBP) is a transcription factor responsible for carbohydrate metabolism in the liver. However, the role of ChREBP in diabetic nephropathy has not been elucidated. Thus, we investigated the role of ChREBP in mesangial cells in diabetic nephropathy. Tre...

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Detalhes bibliográficos
Main Authors: Park, Min-Jung, Kim, Dong-Il, Lim, Seul-Ki, Choi, Joo-Hee, Han, Ho-Jae, Yoon, Kyung-Chul, Park, Soo-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036358/
https://ncbi.nlm.nih.gov/pubmed/24616092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.530139
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