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MicroRNA-9 and MicroRNA-326 Regulate Human Dopamine D2 Receptor Expression, and the MicroRNA-mediated Expression Regulation Is Altered by a Genetic Variant

The human dopamine receptor D2 (DRD2) has been implicated in the pathophysiology of schizophrenia and other neuropsychiatric disorders. Most antipsychotic drugs influence dopaminergic transmission through blocking dopamine receptors, primarily DRD2. We report here the post-transcriptional regulation...

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Hlavní autoři: Shi, Sandra, Leites, Catherine, He, Deli, Schwartz, Daniel, Moy, Winton, Shi, Jianxin, Duan, Jubao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036351/
https://ncbi.nlm.nih.gov/pubmed/24675081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.535203
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