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MicroRNA-9 and MicroRNA-326 Regulate Human Dopamine D2 Receptor Expression, and the MicroRNA-mediated Expression Regulation Is Altered by a Genetic Variant

The human dopamine receptor D2 (DRD2) has been implicated in the pathophysiology of schizophrenia and other neuropsychiatric disorders. Most antipsychotic drugs influence dopaminergic transmission through blocking dopamine receptors, primarily DRD2. We report here the post-transcriptional regulation...

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Detalhes bibliográficos
Main Authors: Shi, Sandra, Leites, Catherine, He, Deli, Schwartz, Daniel, Moy, Winton, Shi, Jianxin, Duan, Jubao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036351/
https://ncbi.nlm.nih.gov/pubmed/24675081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.535203
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