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Nucleotide Interactions of the Human Voltage-dependent Anion Channel

The voltage-dependent anion channel (VDAC) mediates and gates the flux of metabolites and ions across the outer mitochondrial membrane and is a key player in cellular metabolism and apoptosis. Here we characterized the binding of nucleotides to human VDAC1 (hVDAC1) on a single-residue level using NM...

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Détails bibliographiques
Auteurs principaux: Villinger, Saskia, Giller, Karin, Bayrhuber, Monika, Lange, Adam, Griesinger, Christian, Becker, Stefan, Zweckstetter, Markus
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036348/
https://ncbi.nlm.nih.gov/pubmed/24668813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.524173
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