Tight Junctional Localization of Claudin-16 Is Regulated by Syntaxin 8 in Renal Tubular Epithelial Cells

Claudin-16 (CLDN16) regulates the paracellular reabsorption of Mg(2+) in the thick ascending limb of Henle's loop. However, the mechanism regulating the tight junctional localization of CLDN16 remains unknown. In yeast two-hybrid systems, we found that CLDN16 bound to syntaxin 8 (STX8), a targe...

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Detalhes bibliográficos
Main Authors: Ikari, Akira, Tonegawa, Chie, Sanada, Ayumi, Kimura, Toru, Sakai, Hideki, Hayashi, Hisayoshi, Hasegawa, Hajime, Yamaguchi, Masahiko, Yamazaki, Yasuhiro, Endo, Satoshi, Matsunaga, Toshiyuki, Sugatani, Junko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036323/
https://ncbi.nlm.nih.gov/pubmed/24659781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541193
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