A Disease-causing Mutation Illuminates the Protein Membrane Topology of the Kidney-expressed Prohibitin Homology (PHB) Domain Protein Podocin

Mutations in the NPHS2 gene are a major cause of steroid-resistant nephrotic syndrome, a severe human kidney disorder. The NPHS2 gene product podocin is a key component of the slit diaphragm cell junction at the kidney filtration barrier and part of a multiprotein-lipid supercomplex. A similar compl...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Schurek, Eva-Maria, Völker, Linus A., Tax, Judit, Lamkemeyer, Tobias, Rinschen, Markus M., Ungrue, Denise, Kratz, John E., Sirianant, Lalida, Kunzelmann, Karl, Chalfie, Martin, Schermer, Bernhard, Benzing, Thomas, Höhne, Martin
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2014
主題:
Molecular Bases of Disease
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036264/
https://ncbi.nlm.nih.gov/pubmed/24596097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521773
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍