Activated Platelets Interfere with Recruitment of Mesenchymal Stem Cells to Apoptotic Cardiac Cells via High Mobility Group Box 1/Toll-like Receptor 4-mediated Down-regulation of Hepatocyte Growth Factor Receptor MET

Recruitment of mesenchymal stem cells (MSC) following cardiac injury, such as myocardial infarction, plays a critical role in tissue repair and may contribute to myocardial recovery. However, the mechanisms that regulate migration of MSC to the site of tissue damage remain elusive. Here, we demonstr...

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Bibliographic Details
Main Authors: Vogel, Sebastian, Chatterjee, Madhumita, Metzger, Katja, Borst, Oliver, Geisler, Tobias, Seizer, Peter, Müller, Iris, Mack, Andreas, Schumann, Susanne, Bühring, Hans-Jörg, Lang, Florian, Sorg, Rüdiger V., Langer, Harald, Gawaz, Meinrad
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036247/
https://ncbi.nlm.nih.gov/pubmed/24567328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.530287
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