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The Mechanism of Membrane Disruption by Cytotoxic Amyloid Oligomers Formed by Prion Protein(106–126) Is Dependent on Bilayer Composition

The formation of fibrillar aggregates has long been associated with neurodegenerative disorders such as Alzheimer and Parkinson diseases. Although fibrils are still considered important to the pathology of these disorders, it is now widely understood that smaller amyloid oligomers are the toxic enti...

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Opis bibliograficzny
Główni autorzy: Walsh, Patrick, Vanderlee, Gillian, Yau, Jason, Campeau, Jody, Sim, Valerie L., Yip, Christopher M., Sharpe, Simon
Format: Artigo
Język:Inglês
Wydane: American Society for Biochemistry and Molecular Biology 2014
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036164/
https://ncbi.nlm.nih.gov/pubmed/24554723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515866
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