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The application of drug dose equivalence in the quantitative analysis of receptor occupation and drug combinations
In this review we show that the concept of dose equivalence for two drugs, the theoretical basis of the isobologram, has a wider use in the analysis of pharmacological data derived from single and combination drug use. In both its application to drug combination analysis with isoboles and certain ot...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4036078/ https://ncbi.nlm.nih.gov/pubmed/20546783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2010.04.011 |
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