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Single-cell analysis reveals that expression of Nanog is biallelic and equally variable as that of other pluripotency factors in mouse embryonic stem cells

The homeodomain transcription factor Nanog is a central part of the core pluripotency transcriptional network and plays a critical role in embryonic stem (ES) cell self-renewal. Several reports have suggested that Nanog expression is allelically regulated and that transient down-regulation of Nanog...

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Detalhes bibliográficos
Main Authors: Faddah, Dina A., Wang, Haoyi, Cheng, Albert Wu, Katz, Yarden, Buganim, Yosef, Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035816/
https://ncbi.nlm.nih.gov/pubmed/23827708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.04.019
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