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Single-cell analysis reveals that expression of Nanog is biallelic and equally variable as that of other pluripotency factors in mouse embryonic stem cells
The homeodomain transcription factor Nanog is a central part of the core pluripotency transcriptional network and plays a critical role in embryonic stem (ES) cell self-renewal. Several reports have suggested that Nanog expression is allelically regulated and that transient down-regulation of Nanog...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035816/ https://ncbi.nlm.nih.gov/pubmed/23827708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.04.019 |
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