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Signal transmission within the P2X(2) trimeric receptor

P2X(2) receptor channel, a homotrimer activated by the binding of extracellular adenosine triphosphate (ATP) to three intersubunit ATP-binding sites (each located ∼50 Å from the ion permeation pore), also shows voltage-dependent activation upon hyperpolarization. Here, we used tandem trimeric constr...

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Hlavní autoři: Keceli, Batu, Kubo, Yoshihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035740/
https://ncbi.nlm.nih.gov/pubmed/24863932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411166
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