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Functional and structural identification of amino acid residues of the P2X(2) receptor channel critical for the voltage- and [ATP]-dependent gating

The extracellular ATP-gated cation channel P2X(2) is known to show voltage-dependent gating in spite of the absence of a canonical voltage sensor domain. We previously observed that the hyperpolarization-evoked activation of P2X(2) at the steady state in the presence of ATP varied depending on [ATP]...

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Detalhes bibliográficos
Main Authors: Keceli, Batu, Kubo, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808541/
https://ncbi.nlm.nih.gov/pubmed/19884318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.182824
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