Acetylcholine Promotes Binding of α-Conotoxin MII for α(3)β(2) Nicotinic Acetylcholine Receptors

α-Conotoxin MII (α-CTxMII) is a 16 amino acid peptide with the sequence GCCSNPVCHLEHSNLC containing disulfide bonds between Cys2-Cys8 and Cys3-Cys16. This peptide, isolated from the venom of the marine cone snail Conus magus, is a potent and selective antagonist of neuronal nicotinic acetylcholine r...

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Main Authors: Sambasivarao, Somisetti V., Roberts, Jessica, Bharadwaj, Vivek S., Slingsby, Jason G., Rohleder, Conrad, Mallory, Chris, Groome, James R., McDougal, Owen M., Maupin, C. Mark
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035485/
https://ncbi.nlm.nih.gov/pubmed/24420650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300577
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