Inhibition of phosphoinositol 3 kinase contributes to nanoparticle-mediated exaggeration of endotoxin-induced leukocyte procoagulant activity

AIM: Disseminated intravascular coagulation is an increasing concern for certain types of engineered nanomaterials. Recent studies have shed some light on the nanoparticle physicochemical properties contributing to this toxicity; however, the mechanisms are poorly understood. Leukocyte procoagulant...

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Autores principales: Ilinskaya, Anna N, Man, Sonny, Patri, Anil K, Clogston, Jeffrey D, Crist, Rachael M, Cachau, Raul E, McNeil, Scott E, Dobrovolskaia, Marina A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035470/
https://ncbi.nlm.nih.gov/pubmed/24279459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.13.137
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