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Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes
Murine hepatic Cyp4a mRNAs are markedly down-regulated during inflammation. Here we investigated the roles of Cyp4a10 and Cyp4a14 in the response to infection with C. rodentium. Absence of either Cyp4a gene attenuated or abrogated the changes in spleen weight, colon crypt length, hepatic cytokine an...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035451/ https://ncbi.nlm.nih.gov/pubmed/24413902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-013-9809-6 |
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