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Modulation of Hepatic Cytochrome P450s by Citrobacter rodentium Infection in Interleukin-6- and Interferon-γ-Null Mice

After infection with Citrobacter rodentium, murine hepatic cytochrome P450 (P450) mRNAs are selectively regulated. Several serum proinflammatory cytokines are elevated, the most abundant being interleukin-6 (IL6). To elucidate the role of cytokines in the regulation of P450s during infection, we ora...

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書誌詳細
主要な著者: Nyagode, Beatrice A., Lee, Choon-Myung, Morgan, Edward T.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Pharmacology and Experimental Therapeutics 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202470/
https://ncbi.nlm.nih.gov/pubmed/20719939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.171488
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