Macrophages Promote Progression of Spasmolytic Polypeptide-Expressing Metaplasia Following Acute Loss of Parietal Cells

BACKGROUND & AIMS: Loss of parietal cells causes the development of spasmolytic polypeptide-expressing metaplasia (SPEM), through transdifferentiation of chief cells. In the presence of inflammation, SPEM can advance into a more proliferative metaplasia with increased expression of intestine-spe...

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Hauptverfasser: Petersen, Christine P., Weis, Victoria G., Nam, Ki Taek, Sousa, Josane F., Fingleton, Barbara, Goldenring, James R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035414/
https://ncbi.nlm.nih.gov/pubmed/24534633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.02.007
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