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Developmental and Adult GAP-43 Deficiency in Mice Dynamically Alters Hippocampal Neurogenesis and Mossy Fiber Volume

Growth Associated Protein-43 (GAP-43) is a pre-synaptic protein that plays key roles in axonal growth and guidance and in modulating synapse formation. Previous work has demonstrated that mice lacking one allele of this gene [GAP-43(+/-) mice] exhibit hippocampal structural abnormalities and impaire...

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Autori principali: Latchney, Sarah E., Masiulis, Irene, Zaccaria, Kimberly J., Lagace, Diane C., Powell, Craig M., McCasland, James S., Eisch, Amelia J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035301/
https://ncbi.nlm.nih.gov/pubmed/24576816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000357840
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