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Copper(II)-Catalyzed Silylation of Activated Alkynes in Water: Diastereodivergent Access to (E)- or (Z)-β-Silyl-α,β-Unsaturated Carbonyl and Carboxyl Compounds

Copper(II)-catalyzed silylation of substituted alkynylcarbonyl compounds was investigated. Via activation of Me(2)PhSiBpin in water at room temperature and open atmosphere, vinylsilanes conjugated to carbonyl groups are synthesized in high yield. A surprising diastereodivergent access to olefin geom...

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Main Authors: Calderone, Joseph A., Santos, Webster L.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035118/
https://ncbi.nlm.nih.gov/pubmed/24532188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201310695
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