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Technical considerations for genotyping multi-allelic copy number variation (CNV), in regions of segmental duplication
BACKGROUND: Intrachromosomal segmental duplications provide the substrate for non-allelic homologous recombination, facilitating extensive copy number variation in the human genome. Many multi-copy gene families are embedded within genomic regions with high levels of sequence identity (>95%) and...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035060/ https://ncbi.nlm.nih.gov/pubmed/24885186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-329 |
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