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Segmental Duplications and Copy-Number Variation in the Human Genome

The human genome contains numerous blocks of highly homologous duplicated sequence. This higher-order architecture provides a substrate for recombination and recurrent chromosomal rearrangement associated with genomic disease. However, an assessment of the role of segmental duplications in normal va...

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Autors principals: Sharp, Andrew J. , Locke, Devin P. , McGrath, Sean D. , Cheng, Ze , Bailey, Jeffrey A. , Vallente, Rhea U. , Pertz, Lisa M. , Clark, Royden A. , Schwartz, Stuart , Segraves, Rick , Oseroff, Vanessa V. , Albertson, Donna G. , Pinkel, Daniel , Eichler, Evan E. 
Format: Artigo
Idioma:Inglês
Publicat: American Society of Human Genetics 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1226196/
https://ncbi.nlm.nih.gov/pubmed/15918152
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