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Brain delivery of proteins via their fatty acid and block copolymer modifications
It is well known that hydrophobic small molecules penetrate cell membranes better than hydrophilic molecules. Amphiphilic molecules that dissolve both in lipid and aqueous phases are best suited for membrane transport. Transport of biomacromolecules across physiological barriers, e.g. the blood-brai...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035013/ https://ncbi.nlm.nih.gov/pubmed/24160902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1061186X.2013.847098 |
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