Resveratrol Counteracts Inflammation in Human M1 and M2 Macrophages upon Challenge with 7-Oxo-Cholesterol: Potential Therapeutic Implications in Atherosclerosis

Macrophages consist of two main subsets: the proinflammatory M1 subset and the anti-inflammatory M2 one. 7-oxo-cholesterol, the most abundant cholesterol autoxidation product within atherosclerotic plaque, is able to skew the M1/M2 balance towards a proinflammatory profile. In the present study, we...

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Detalhes bibliográficos
Main Authors: Buttari, Brigitta, Profumo, Elisabetta, Segoni, Luca, D'Arcangelo, Daniela, Rossi, Stefania, Facchiano, Francesco, Saso, Luciano, Businaro, Rita, Iuliano, Luigi, Riganò, Rachele
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034709/
https://ncbi.nlm.nih.gov/pubmed/24895526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/257543
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