Lupeol Counteracts the Proinflammatory Signalling Triggered in Macrophages by 7-Keto-Cholesterol: New Perspectives in the Therapy of Atherosclerosis

Macrophage activation and polarization play a central role in atherosclerotic plaque fate. The M1/M2 activation phenotypes represent two profiles of the macrophage polarization state. During atherosclerosis regression or stabilization, macrophages switch from M1 proinflammatory phenotype to M2 anti-...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Saha, Sarmistha, Profumo, Elisabetta, Togna, Anna Rita, Riganò, Rachele, Saso, Luciano, Buttari, Brigitta
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7537694/
https://ncbi.nlm.nih.gov/pubmed/33062133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/1232816
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