In Silico Investigation of Cytochrome P450 2C9 in relation to Aging Using Traditional Chinese Medicine

Cytochrome P450 2C9 (CYP2C9) metabolizes dehydroepiandrosterone-sulfate (DHEA-S), but in elderly people the amount of DHEA-S remaining after CYP2C9 metabolization may be insufficient for optimal health. A prediction model, molecular docking, and molecular dynamics were used to screen the Traditional...

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Bibliografiske detaljer
Main Authors: Hung, Tzu-Chieh, Kuo, Chia-Chen, Chen, Calvin Yu-Chian
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034651/
https://ncbi.nlm.nih.gov/pubmed/24899908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/404505
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