Stromal-mediated protection of tyrosine kinase inhibitor-treated BCR-ABL-expressing leukemia cells

Clinical studies of patients with chronic myeloid leukemia (CML) revealed that a common pattern of response is a dramatic fall in the circulating population of blast cells, with a minimal or delayed decrease in marrow blasts, suggesting a protective environment. These observations suggest that a gre...

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Bibliographic Details
Main Authors: Weisberg, Ellen, Wright, Renee D., McMillin, Douglas W., Mitsiades, Constantine, Ray, Arghya, Barrett, Rosemary, Adamia, Sophia, Stone, Richard, Galinsky, Ilene, Kung, Andrew L., Griffin, James D.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034541/
https://ncbi.nlm.nih.gov/pubmed/18445657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2331
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