Involvement of the Circadian Rhythm and Inflammatory Cytokines in the Pathogenesis of Rheumatoid Arthritis

Among the symptoms of patients with rheumatoid arthritis (RA), joint stiffness is influenced by diurnal rhythm and reaches peak in the morning, which is a common complaint and reflects the circadian nature of disease manifestation. In addition, inflammatory cytokines, which reach peak secretion earl...

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Bibliographic Details
Main Authors: Yoshida, Kohsuke, Hashimoto, Teppei, Sakai, Yoshitada, Hashiramoto, Akira
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034483/
https://ncbi.nlm.nih.gov/pubmed/24901009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/282495
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