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Involvement of the Circadian Rhythm and Inflammatory Cytokines in the Pathogenesis of Rheumatoid Arthritis

Among the symptoms of patients with rheumatoid arthritis (RA), joint stiffness is influenced by diurnal rhythm and reaches peak in the morning, which is a common complaint and reflects the circadian nature of disease manifestation. In addition, inflammatory cytokines, which reach peak secretion earl...

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Detalhes bibliográficos
Main Authors: Yoshida, Kohsuke, Hashimoto, Teppei, Sakai, Yoshitada, Hashiramoto, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034483/
https://ncbi.nlm.nih.gov/pubmed/24901009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/282495
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