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Inhibition of phosphodiesterase 4 reduces ethanol intake and preference in C57BL/6J mice
Some anti-inflammatory medications reduce alcohol consumption in rodent models. Inhibition of phosphodiesterases (PDE) increases cAMP and reduces inflammatory signaling. Rolipram, an inhibitor of PDE4, markedly reduced ethanol intake and preference in mice and reduced ethanol seeking and consumption...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034339/ https://ncbi.nlm.nih.gov/pubmed/24904269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00129 |
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