Role of Interleukin-1 Receptor Signaling in the Behavioral Effects of Ethanol and Benzodiazepines

Gene expression studies identified the interleukin-1 receptor type I (IL-1R1) as part of a pathway associated with a genetic predisposition to high alcohol consumption, and lack of the endogenous IL-1 receptor antagonist (IL-1ra) strongly reduced ethanol intake in mice. Here, we compared ethanol-med...

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Udgivet i:Neuropharmacology
Main Authors: Blednov, Yuri A., Benavidez, Jillian M., Black, Mendy, Mayfield, Jody, Harris, R. Adron
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465986/
https://ncbi.nlm.nih.gov/pubmed/25839897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.03.015
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