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Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection

CD4 T cells are central to orchestrate, sustain, and potentially regenerate antiviral immunity throughout persistent viral infections. Although the evolving immune environment during persistent infection reshapes established CD4 T-cell responses, the fate of naïve CD4 T cells primed in the midst of...

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Detalhes bibliográficos
Main Authors: Osokine, Ivan, Snell, Laura M., Cunningham, Cameron R., Yamada, Douglas H., Wilson, Elizabeth B., Elsaesser, Heidi J., de la Torre, Juan Carlos, Brooks, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034239/
https://ncbi.nlm.nih.gov/pubmed/24799699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401662111
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