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High-throughput platform for the discovery of elicitors of silent bacterial gene clusters

Over the past decade, bacterial genome sequences have revealed an immense reservoir of biosynthetic gene clusters, sets of contiguous genes that have the potential to produce drugs or drug-like molecules. However, the majority of these gene clusters appear to be inactive for unknown reasons promptin...

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Hlavní autor: Seyedsayamdost, Mohammad R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034229/
https://ncbi.nlm.nih.gov/pubmed/24808135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400019111
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