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High-throughput platform for the discovery of elicitors of silent bacterial gene clusters
Over the past decade, bacterial genome sequences have revealed an immense reservoir of biosynthetic gene clusters, sets of contiguous genes that have the potential to produce drugs or drug-like molecules. However, the majority of these gene clusters appear to be inactive for unknown reasons promptin...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
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National Academy of Sciences
2014
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034229/ https://ncbi.nlm.nih.gov/pubmed/24808135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400019111 |
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