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Identification of the 11-cis-specific retinyl-ester synthase in retinal Müller cells as multifunctional O-acyltransferase (MFAT)

Absorption of a photon by a rhodopsin or cone-opsin pigment isomerizes its 11-cis-retinaldehyde (11-cis-RAL) chromophore to all-trans-retinaldehyde (all-trans-RAL), which dissociates after a brief period of activation. Light sensitivity is restored to the resulting apo-opsin when it recombines with...

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Bibliografische gegevens
Hoofdauteurs: Kaylor, Joanna J., Cook, Jeremy D., Makshanoff, Jacob, Bischoff, Nicholas, Yong, Jennifer, Travis, Gabriel H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034218/
https://ncbi.nlm.nih.gov/pubmed/24799687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319142111
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