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myosin 7aa(−/−) mutant zebrafish show mild photoreceptor degeneration and reduced electroretinographic responses
Mutations in myosin VIIa (MYO7A) cause Usher syndrome 1B (USH1B), a disease characterized by the combination of sensorineural hearing loss and visual impairment termed retinitis pigmentosa (RP). Although the shaker-1 mouse model of USH1B exists, only minor defects in the retina have been observed du...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034177/ https://ncbi.nlm.nih.gov/pubmed/24698764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2014.03.007 |
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