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Noncell-autonomous photoreceptor degeneration in a zebrafish model of choroideremia
Choroideremia is an X-linked hereditary retinal degeneration resulting from mutations in the Rab escort protein-1 (REP1). The Rep1 protein facilitates posttranslational modification of Rab proteins, which regulate intracellular trafficking in the retinal pigment epithelium (RPE) and photoreceptors a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1810335/ https://ncbi.nlm.nih.gov/pubmed/17360570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605818104 |
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