Positive effects of methylphenidate on hyperactivity are moderated by monoaminergic gene variants in children with autism spectrum disorders

Methylphenidate (MPH) reduces hyperactive-impulsive symptoms common in children with autism spectrum disorders (ASDs), however, response and tolerability varies widely. We hypothesized monoaminergic gene variants may moderate MPH effects in ASD, as in typically developing children with attention-def...

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Autors principals: McCracken, J T, Badashova, K K, Posey, D J, Aman, M G, Scahill, L, Tierney, E, Arnold, L E, Vitiello, B, Whelan, F, Chuang, S Z, Davies, M, Shah, B, McDougle, C J, Nurmi, E L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034115/
https://ncbi.nlm.nih.gov/pubmed/23856854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2013.23
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