Possible Influence of Variant of the P-Glycoprotein Gene (MDR1/ABCB1) on Clinical Response to Guanfacine in Children with Pervasive Developmental Disorders and Hyperactivity

OBJECTIVE: Guanfacine has been shown to reduce hyperactive behaviors in children with attention-deficit/hyperactivity disorder (ADHD) and possibly in children with pervasive developmental disorder (PDD) and hyperactivity. The aim of this exploratory study was to examine whether gene variants encodin...

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Detalhes bibliográficos
Main Authors: McCracken, James T., Aman, Michael G., McDougle, Christopher J., Tierney, Elaine, Shiraga, Sharon, Whelan, Fiona, Arnold, L. Eugene, Posey, David, Ritz, Louise, Vitiello, Benedetto, Scahill, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835389/
https://ncbi.nlm.nih.gov/pubmed/20166790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cap.2009.0059
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