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Synthetic Medicinal Chemistry in Chagas’ Disease: Compounds at The Final Stage of “Hit-To-Lead” Phase

Chagas’ disease, or American trypanosomosiasis, has been the most relevant illness produced by protozoa in Latin America. Synthetic medicinal chemistry efforts have provided an extensive number of chemodiverse hits at the “active-to-hit” stage. However, only a more limited number of these have been...

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Autors principals: Cerecetto, Hugo, González, Mercedes
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034012/
https://ncbi.nlm.nih.gov/pubmed/27713281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3040810
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