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Update on the Genetic Polymorphisms of Drug-Metabolizing Enzymes in Antiepileptic Drug Therapy

Genetic polymorphisms in the genes that encode drug-metabolizing enzymes are implicated in the inter-individual variability in the pharmacokinetics and pharmaco-dynamics of antiepileptic drugs (AEDs). However, the clinical impact of these polymorphisms on AED therapy still remains controversial. The...

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Autors principals: Saruwatari, Junji, Ishitsu, Takateru, Nakagawa, Kazuko
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033946/
https://ncbi.nlm.nih.gov/pubmed/27713373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3082709
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